tert-Butylhydroquinone (TBHQ) (E319) β€” What You Need to Know

Questionable(4/10)Synthetic

The score is an eNumbers.org editorial summary, not an official agency rating or medical advice. Start with the regulatory status and primary sources below.

What Is tert-Butylhydroquinone (TBHQ)?

TBHQ is a synthetic antioxidant derived from hydroquinone, used primarily to extend the shelf life of oils and fat-containing processed foods. It is not authorized as a food additive in the EU or Japan, but is permitted in the United States and several other countries at limited concentrations. It is one of the more controversial synthetic antioxidants still in widespread use.

What Is It Used For?

Prevents oxidation and rancidity in cooking oils, fried foods, and fat-containing snack products. Commonly found in US fast food and packaged food products.

Function: Antioxidant, fat preservative
0.2 mg
Dataset exposure estimate
49 mg
ADI-derived reference (70 kg)
0.4%
of ADI (typical diet)

Exposure figures are population-level references, not personal limits. Actual intake varies by diet, product and jurisdiction.

Regulatory & Editorial Context

πŸ“Š
Acceptable Daily Intake (ADI)
0.7 mg/kg bw/day
πŸ›οΈ
Regulatory Status
πŸ‡ͺπŸ‡Ί EU: Not authorized
πŸ‡ΊπŸ‡Έ US: Approved
πŸ‡―πŸ‡΅ JP: Approved
πŸ‡¦πŸ‡Ί AU: Approved
πŸ‡¨πŸ‡¦ CA: Approved
⚠️ Key Concerns

Not authorized in the EU as a food additive. FDA allows use up to 0.02% of fat content. High doses in animal studies caused stomach tumors in rats and damage to DNA. Some studies link to immune system effects β€” a 2019 EWG report highlighted concerns about TBHQ affecting immune response. NTP found equivocal evidence of carcinogenicity. Often used in US fast food and snack products where it is absent from EU equivalents. Consumer advocacy groups like CSPI recommend avoiding it.

Editorial context score

eNumbers.org currently assigns tert-Butylhydroquinone (TBHQ) an editorial context label of Questionable with a score of 4/10. This is 3.1 points below the database average for antioxidants (7.1/10). Dataset reference year: 2019. The dataset's population estimate equals about 0.4% of the listed ADI.

This score is not issued by EFSA, FDA, WHO or another regulator.

Commonly Found In

Cooking oilsFrozen fishChicken nuggetsCrackersMicrowave popcornSnack foods
Example brands:
McDonald's (US)Cheez-ItPop Secret

Always check the label for E319 or 'tert-Butylhydroquinone (TBHQ)'

β–ΆChemical Information
Formula: C10H14O2
Molecular Weight: 166.22 g/mol
CAS Number: 1948-33-0
INS Number: 319
Also known as: E319, INS 319, TBHQ, tert-Butylhydroquinone, Tertiary butylhydroquinone, Mono-tert-butylhydroquinone

Frequently Asked Questions about tert-Butylhydroquinone (TBHQ)

Current dataset status: FDA β€” Approved; EFSA/EU β€” Not authorized. Reported concerns: Not authorized in the EU as a food additive. FDA allows use up to 0.02% of fat content. High doses in animal studies caused stomach tumors in rats and damage to DNA. Some studies link to immune system effects β€” a 2019 EWG report highlighted concerns about TBHQ affecting immune response. NTP found equivocal evidence of carcinogenicity. Often used in US fast food and snack products where it is absent from EU equivalents. Consumer advocacy groups like CSPI recommend avoiding it. Regulatory status and individual risk are not the same; check the primary sources and permitted conditions of use.

Quick Facts

E-Number
E319
INS Number
319
Category
Antioxidants
Origin
Synthetic
FDA Status
Approved
EFSA Status
Not authorized
ADI
0.7 mg/kg bw/day
Dataset Review
2019
Ingredient-level Dietary Notes
Vegan: βœ… YesHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes

Carriers, processing aids and product certification can change suitability. Verify the final label and certifier.

Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.

Related Additives

Other antioxidants in the same family