Tocopherols (Vitamin E) (E306) β€” What You Need to Know

Safe(9/10)Natural

The score is an eNumbers.org editorial summary, not an official agency rating or medical advice. Start with the regulatory status and primary sources below.

What Is Tocopherols (Vitamin E)?

Tocopherols are a family of vitamin E compounds found naturally in vegetable oils, nuts, seeds, and green leafy vegetables. As food additives, they serve primarily as antioxidants to prevent rancidity in fats and oils. There are four forms of tocopherol: alpha, beta, gamma, and delta. Alpha-tocopherol (E307) is the most biologically active form as vitamin E. When used in food, they provide the dual benefit of preservation and nutritional fortification.

What Is It Used For?

Prevents oxidation and rancidity in oils, fats, nuts, and foods with high fat content. Also used to fortify foods with vitamin E. Found naturally in many plant foods and added to processed foods to extend shelf life.

Function: Antioxidant, nutrient supplement
15 mg
Dataset exposure estimate
10 mg
ADI-derived reference (70 kg)
142.9%
of ADI (typical diet)

Exposure figures are population-level references, not personal limits. Actual intake varies by diet, product and jurisdiction.

Regulatory & Editorial Context

πŸ“Š
Acceptable Daily Intake (ADI)
0.15-2 mg/kg bw/day (as alpha-tocopherol equivalent)
πŸ›οΈ
Regulatory Status
πŸ‡ΊπŸ‡Έ USA (FDA): GRAS
πŸ‡ͺπŸ‡Ί EU (EFSA): Authorized
⚠️ Key Concerns

Extremely safe as a food additive. High-dose supplemental vitamin E (above 400 IU/day) has been associated with slightly increased all-cause mortality in some meta-analyses, but this is only relevant to high-dose supplements, not food additive levels. No concerns at normal dietary or additive levels.

Editorial context score

eNumbers.org currently assigns Tocopherols (Vitamin E) an editorial context label of Safe with a score of 9/10. This is 1.9 points above the database average for antioxidants (7.1/10). Dataset reference year: 2015. The dataset's population estimate equals about 142.9% of the listed ADI.

This score is not issued by EFSA, FDA, WHO or another regulator.

Commonly Found In

Vegetable oilsMargarineNutsCerealsInfant formulaSports nutrition

Always check the label for E306 or 'Tocopherols (Vitamin E)'

β–ΆChemical Information
CAS Number: 10191-41-0
INS Number: 306
Also known as: E306, E307, E308, E309, INS 306, Vitamin E, Mixed tocopherols, Alpha-tocopherol

Frequently Asked Questions about Tocopherols (Vitamin E)

Current dataset status: FDA β€” GRAS; EFSA/EU β€” Authorized. Reported concerns: Extremely safe as a food additive. High-dose supplemental vitamin E (above 400 IU/day) has been associated with slightly increased all-cause mortality in some meta-analyses, but this is only relevant to high-dose supplements, not food additive levels. No concerns at normal dietary or additive levels. Regulatory status and individual risk are not the same; check the primary sources and permitted conditions of use.

Quick Facts

E-Number
E306
INS Number
306
Category
Antioxidants
Origin
Natural
FDA Status
GRAS
EFSA Status
Authorized
ADI
0.15-2 mg/kg bw/day (as alpha-tocopherol equivalent)
Dataset Review
2015
Ingredient-level Dietary Notes
Vegan: βœ… YesHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes

Carriers, processing aids and product certification can change suitability. Verify the final label and certifier.

Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.

Related Additives

Other antioxidants in the same family