Sucralose (E955) β€” What You Need to Know

Caution(6/10)Synthetic

The score is an eNumbers.org editorial summary, not an official agency rating or medical advice. Start with the regulatory status and primary sources below.

What Is Sucralose?

Sucralose is a synthetic sweetener made by chlorinating sucrose (table sugar). It is approximately 600 times sweeter than sugar and passes through the body mostly unabsorbed. It was discovered in 1976 at Queen Elizabeth College, London. Splenda is the best-known brand. Unlike aspartame, sucralose is heat-stable and can be used in baking.

What Is It Used For?

Used in diet drinks, baked goods, dairy products, and tabletop sweeteners. It is heat-stable making it suitable for cooking and baking, which is an advantage over aspartame.

Function: Intense artificial sweetener

Regulatory & Editorial Context

πŸ“Š
Acceptable Daily Intake (ADI)
15 mg/kg bw/day
πŸ›οΈ
Regulatory Status
πŸ‡ΊπŸ‡Έ USA (FDA): Approved
πŸ‡ͺπŸ‡Ί EU (EFSA): Authorized
⚠️ Key Concerns

Recent research has raised some concerns. A 2023 study published in Nature Medicine found sucralose-6-acetate (a metabolite and trace contaminant in sucralose) to be genotoxic in vitro. A 2023 study also found higher cardiovascular risk associated with sucralose consumption. Some research suggests sucralose may negatively affect gut microbiome diversity at high doses. The FDA and EFSA still consider sucralose safe based on current evidence, but these emerging findings warrant monitoring. Earlier concerns about high-heat cooking producing potentially harmful chlorinated compounds have been raised but not conclusively established at normal cooking temperatures.

Editorial context score

eNumbers.org currently assigns Sucralose an editorial context label of Caution with a score of 6/10. This is 0.2 points above the database average for sweeteners (5.8/10). Dataset reference year: 2017.

This score is not issued by EFSA, FDA, WHO or another regulator.

Commonly Found In

Diet sodaBaked goodsProtein barsYogurtIce cream
Example brands:
SplendaDiet Coke with Splenda

Always check the label for E955 or 'Sucralose'

β–ΆChemical Information
Formula: C12H19Cl3O8
Molecular Weight: 397.63 g/mol
CAS Number: 56038-13-2
INS Number: 955
Also known as: E955, INS 955, Splenda, Trichlorogalactosucrose, TGS

Primary Sources

Source review: 2026-08-08

Official references relevant to this page. Check the agency record for current permitted uses, limits and jurisdiction-specific wording.

How eNumbers.org uses sources β†’

Frequently Asked Questions about Sucralose

Current dataset status: FDA β€” Approved; EFSA/EU β€” Authorized. Reported concerns: Recent research has raised some concerns. A 2023 study published in Nature Medicine found sucralose-6-acetate (a metabolite and trace contaminant in sucralose) to be genotoxic in vitro. A 2023 study also found higher cardiovascular risk associated with sucralose consumption. Some research suggests sucralose may negatively affect gut microbiome diversity at high doses. The FDA and EFSA still consider sucralose safe based on current evidence, but these emerging findings warrant monitoring. Earlier concerns about high-heat cooking producing potentially harmful chlorinated compounds have been raised but not conclusively established at normal cooking temperatures. Regulatory status and individual risk are not the same; check the primary sources and permitted conditions of use.

Quick Facts

E-Number
E955
INS Number
955
Category
Sweeteners
Origin
Synthetic
FDA Status
Approved
EFSA Status
Authorized
ADI
15 mg/kg bw/day
Dataset Review
2017
Ingredient-level Dietary Notes
Vegan: βœ… YesHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes

Carriers, processing aids and product certification can change suitability. Verify the final label and certifier.

Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.

Related Additives

Other sweeteners in the same family