Sucralose (E955) β€” What You Need to Know

Caution(6/10)Synthetic
6
CAUTION
Safety Score: 6/10

What Is Sucralose?

Sucralose is a synthetic sweetener made by chlorinating sucrose (table sugar). It is approximately 600 times sweeter than sugar and passes through the body mostly unabsorbed. It was discovered in 1976 at Queen Elizabeth College, London. Splenda is the best-known brand. Unlike aspartame, sucralose is heat-stable and can be used in baking.

What Is It Used For?

Used in diet drinks, baked goods, dairy products, and tabletop sweeteners. It is heat-stable making it suitable for cooking and baking, which is an advantage over aspartame.

Function: Intense artificial sweetener

Safety Assessment

πŸ“Š
Acceptable Daily Intake (ADI)
15 mg/kg bw/day
πŸ›οΈ
Regulatory Status
πŸ‡ΊπŸ‡Έ USA (FDA): Approved
πŸ‡ͺπŸ‡Ί EU (EFSA): Authorized
⚠️ Key Concerns

Recent research has raised some concerns. A 2023 study published in Nature Medicine found sucralose-6-acetate (a metabolite and trace contaminant in sucralose) to be genotoxic in vitro. A 2023 study also found higher cardiovascular risk associated with sucralose consumption. Some research suggests sucralose may negatively affect gut microbiome diversity at high doses. The FDA and EFSA still consider sucralose safe based on current evidence, but these emerging findings warrant monitoring. Earlier concerns about high-heat cooking producing potentially harmful chlorinated compounds have been raised but not conclusively established at normal cooking temperatures.

Our Assessment

Based on current evidence, Sucralose is rated Caution with a score of 6/10. This is 0.2 points above the average for sweeteners (5.8/10). Last reviewed by regulators: 2017.

Commonly Found In

Diet sodaBaked goodsProtein barsYogurtIce cream
Example brands:
SplendaDiet Coke with Splenda

Always check the label for E955 or 'Sucralose'

β–ΆChemical Information
Formula: C12H19Cl3O8
Molecular Weight: 397.63 g/mol
CAS Number: 56038-13-2
INS Number: 955
Also known as: E955, INS 955, Splenda, Trichlorogalactosucrose, TGS

Frequently Asked Questions about Sucralose

Sucralose has a Safety Score of 6/10 (Caution). Recent research has raised some concerns. A 2023 study published in Nature Medicine found sucralose-6-acetate (a metabolite and trace contaminant in sucralose) to be genotoxic in vitro. A 2023 study also found higher cardiovascular risk associated with sucralose consumption. Some research suggests sucralose may negatively affect gut microbiome diversity at high doses. The FDA and EFSA still consider sucralose safe based on current evidence, but these emerging findings warrant monitoring. Earlier concerns about high-heat cooking producing potentially harmful chlorinated compounds have been raised but not conclusively established at normal cooking temperatures.

Quick Facts

E-Number
E955
INS Number
955
Category
Sweeteners
Origin
Synthetic
FDA Status
Approved
EFSA Status
Authorized
ADI
15 mg/kg bw/day
Last Review
2017
Dietary Compatibility
Vegan: βœ… YesHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes
Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.

Related Additives

Other sweeteners in the same family