Sodium Sulphite (E221) β€” What You Need to Know

Caution(5/10)Synthetic
5
CAUTION
Safety Score: 5/10

What Is Sodium Sulphite?

Sodium sulphite is an inorganic compound used as a preservative and antioxidant in the food industry. It releases sulphur dioxide (SO2) in solution, which is the active antimicrobial and antioxidant agent. It is part of the sulphite group of preservatives (E220–E228) that have been used in food preservation for centuries.

What Is It Used For?

Used to prevent browning and microbial spoilage in dried fruits, wines, and dehydrated vegetables. Acts as both an antioxidant and antimicrobial agent, and is also used as a bleaching agent in some food processing applications.

Function: Preservative, antioxidant, bleaching agent

Safety Assessment

πŸ“Š
Acceptable Daily Intake (ADI)
0.7 mg/kg bw/day
πŸ›οΈ
Regulatory Status
πŸ‡ΊπŸ‡Έ USA (FDA): GRAS (with mandatory labeling above 10 ppm)
πŸ‡ͺπŸ‡Ί EU (EFSA): Authorized β€” group ADI as SO2 for all sulphites (E220–E228)
⚠️ Key Concerns

Part of the sulphite group (E220–E228). Sulphites can trigger severe asthmatic reactions in sulphite-sensitive individuals (estimated 3-10% of asthmatic patients). FDA mandates labeling when sulphites exceed 10 ppm. Sulphites destroy vitamin B1 (thiamine). EFSA lowered the group ADI from 0.7 to 0.7 mg SO2/kg bw/day in 2016 after finding exposure frequently exceeded ADI.

Our Assessment

Based on current evidence, Sodium Sulphite is rated Caution with a score of 5/10. This is 0.7 points below the average for preservatives (5.7/10). Last reviewed by regulators: 2016.

Commonly Found In

Dried fruitsWineShrimpDehydrated vegetablesFruit juices
Example brands:
Sun-MaidOcean Spray

Always check the label for E221 or 'Sodium Sulphite'

β–ΆChemical Information
Formula: Na2SO3
Molecular Weight: 126.04 g/mol
CAS Number: 7757-83-7
INS Number: 221
Also known as: E221, INS 221, Sodium sulfite

Frequently Asked Questions about Sodium Sulphite

Sodium Sulphite has a Safety Score of 5/10 (Caution). Part of the sulphite group (E220–E228). Sulphites can trigger severe asthmatic reactions in sulphite-sensitive individuals (estimated 3-10% of asthmatic patients). FDA mandates labeling when sulphites exceed 10 ppm. Sulphites destroy vitamin B1 (thiamine). EFSA lowered the group ADI from 0.7 to 0.7 mg SO2/kg bw/day in 2016 after finding exposure frequently exceeded ADI.

Quick Facts

E-Number
E221
INS Number
221
Origin
Synthetic
FDA Status
GRAS (with mandatory labeling above 10 ppm)
EFSA Status
Authorized β€” group ADI as SO2 for all sulphites (E220–E228)
ADI
0.7 mg/kg bw/day
Last Review
2016
Dietary Compatibility
Vegan: βœ… YesHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes
Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.

Related Additives

Other preservatives in the same family