Disodium Guanylate (E627) β€” What You Need to Know

Generally Safe(7/10)Unknown

The score is an eNumbers.org editorial summary, not an official agency rating or medical advice. Start with the regulatory status and primary sources below.

What Is Disodium Guanylate?

Flavour enhancer that works synergistically with MSG to intensify umami taste. Derived from yeast extract or sardines.

What Is It Used For?

Function:
0.5 mg
Dataset exposure estimate

Exposure figures are population-level references, not personal limits. Actual intake varies by diet, product and jurisdiction.

Regulatory & Editorial Context

πŸ“Š
Acceptable Daily Intake (ADI)
Not specified
πŸ›οΈ
Regulatory Status
πŸ‡ΊπŸ‡Έ USA (FDA): GRAS
πŸ‡ͺπŸ‡Ί EU (EFSA): Approved
Editorial context score

eNumbers.org currently assigns Disodium Guanylate an editorial context label of Generally Safe with a score of 7/10. This is 0.2 points below the database average for flavor enhancers (7.2/10). Dataset reference year: .

This score is not issued by EFSA, FDA, WHO or another regulator.

Commonly Found In

Instant noodlesCrispsSnack seasoningStock cubesSauces

Always check the label for E627 or 'Disodium Guanylate'

β–ΆChemical Information
Formula: C₁₀H₁₂Nβ‚…Naβ‚‚Oβ‚ˆP
CAS Number: 5550-12-9
INS Number: 627
Also known as: E627, INS 627, GMP, Disodium 5'-guanylate

Frequently Asked Questions about Disodium Guanylate

Current dataset status: FDA β€” GRAS; EFSA/EU β€” Approved. Regulatory status can change and does not replace personal medical advice.

Quick Facts

E-Number
E627
INS Number
627
Origin
Unknown
FDA Status
GRAS
EFSA Status
Approved
ADI
Not specified
Dataset Review
Ingredient-level Dietary Notes
Vegan: ❌ NoHalal: βœ… YesKosher: βœ… YesGluten-Free: βœ… Yes

Carriers, processing aids and product certification can change suitability. Verify the final label and certifier.

Disclaimer: This information is for educational purposes only and is not medical advice. Always consult a healthcare professional for health-related decisions.